Thesis

83 Incidence Peaks and the Role of Influenza Appendix B Clinical diagnosis definitions (in addition to those adhering to ICSD-3 criteria) Clinical diagnosis of NT1: people with a hypocretin-1 level between 110 and 150, or people with typical cataplexy and a multiple sleep latency test sleep latency between eight and 12 minutes or just one sleep-onset rapid eye movement (REM) period. Clinical diagnosis of NT2: people without cataplexy, at least two sleep-onset REM periods and a sleep latency between eight and 12 minutes. Clinical diagnosis of IH: people without cataplexy, fewer than two sleep-onset REM periods and a sleep latency between eight and 12 minutes. Number of subjects per center Supplementary Table 1: Inclusions per center Location Narcolepsy type 1 Narcolepsy type 2 Idiopathic hypersomnia All Children Adults All Children Adults All Children Adults Heemstede, the Netherlands 221 161 60 23 12 11 51 29 22 Bologna, Italy 160 92 68 25 14 11 61 21 40 Montpellier, France 332 190 142 109 67 42 178 103 75 Prague, Czech Republic 98 53 44 27 14 13 31 13 18 Warsaw, Poland 944648- - - - - - Innsbruck, Austria 29-------- Kosice, Slovak Republic 27 11 14 5 2 3 5 1 4 Madrid, Spain 201010- - - 144 10 3

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