363 References 56. Partinen M, Saarenpaa-Heikkila O, Ilveskoski I, Hublin C, Linna M, Olsen P, et al. Increased incidence and clinical picture of childhood narcolepsy following the 2009 H1N1 pandemic vaccination campaign in Finland. PLoS One. 2012;7(3):e33723. 57. Wijnans L, Lecomte C, de Vries C, Weibel D, Sammon C, Hviid A, et al. The incidence of narcolepsy in Europe: before, during, and after the influenza A(H1N1)pdm09 pandemic and vaccination campaigns. Vaccine. 2013;31(8):1246-54. 58. Huang WT, Huang YS, Hsu CY, Chen HC, Lee HC, Lin HC, et al. Narcolepsy and 2009 H1N1 pandemic vaccination in Taiwan. Sleep Med. 2020;66:276-81. 59. Simakajornboon N, Mignot E, Maski K, Owens J, Rosen C, Ibrahim S, et al. Increased incidence of pediatric narcolepsy following the 2009 H1N1 pandemic: a report from the pediatric working group of the sleep research network. Sleep. 2022;45(9). 60. Han F, Lin L, Warby SC, Faraco J, Li J, Dong SX, et al. Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in China. Ann Neurol. 2011;70(3):410-7. 61. Gool JK, Schinkelshoek MS, Fronczek R. What triggered narcolepsy: H1N1 vaccination, virus, or both? Important lessons learned from China. Sleep. 2023;46(3). 62. Morens DM, Taubenberger JK, Fauci AS. The persistent legacy of the 1918 influenza virus. N Engl J Med. 2009;361(3):225-9. 63. Longstreth WT, Jr., Ton TG, Koepsell TD. Narcolepsy and streptococcal infections. Sleep. 2009;32(12):1548. 64. Lopes DA, Coelho FM, Pradella-Hallinan M, de Araujo Melo MH, Tufik S. Infancy narcolepsy: Streptococcus infection as a causal factor. Sleep Sci. 2015;8(1):49-52. 65. Aran A, Lin L, Nevsimalova S, Plazzi G, Hong SC, Weiner K, et al. Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset. Sleep. 2009;32(8):979-83. 66. Koepsell TD, Longstreth WT, Ton TG. Medical exposures in youth and the frequency of narcolepsy with cataplexy: a population-based case-control study in genetically predisposed people. J Sleep Res. 2010;19(1 Pt 1):80-6. 67. Natarajan N, Jain SV, Chaudhry H, Hallinan BE, Simakajornboon N. Narcolepsycataplexy: is streptococcal infection a trigger? J Clin Sleep Med. 2013;9(3):269-70. 68. Latorre D, Kallweit U, Armentani E, Foglierini M, Mele F, Cassotta A, et al. T cells in patients with narcolepsy target self-antigens of hypocretin neurons. Nature. 2018;562(7725):63-8. 69. Luo G, Zhang J, Lin L, Mignot EJ. Characterization of T cell receptors reactive to HCRT(NH2), pHA(273-287), and NP(17-31) in control and narcolepsy patients. Proc Natl Acad Sci U S A. 2022;119(32):e2205797119. 70. Viste R, Lie BA, Viken MK, Rootwelt T, Knudsen-Heier S, Kornum BR. Narcolepsy type 1 patients have lower levels of effector memory CD4(+) T cells compared to their siblings when controlling for H1N1-(Pandemrix)-vaccination and HLA DQB1 *06:02 status. Sleep Med. 2021;85:271-9. 71. Schinkelshoek MS, Fronczek R, Kooy-Winkelaar EMC, Petersen J, Reid HH, van der Heide A, et al. H1N1 hemagglutinin-specific HLA-DQ6-restricted CD4+ T cells can be readily detected in narcolepsy type 1 patients and healthy controls. J Neuroimmunol. 2019;332:167-75. 72. Bernard-Valnet R, Yshii L, Queriault C, Nguyen XH, Arthaud S, Rodrigues M, et al. CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice. Proc Natl Acad Sci U S A. 2016;113(39):10956-61. 12
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