253 Clustering in Central Disorders of Hypersomnolence People without cataplexy were generally grouped into clusters 5 and 6 (157 and 158 people, respectively). As displayed in Table 2, individuals in cluster 5 presented with significantly more sleep drunkenness, subjective difficulty in awakening, memory complaints, fatigue, and larger weekend to week sleep length difference compared to those in cluster 6. In addition, cluster 6 had a relatively higher percentage of HLA-DQB1*0602 positivity and lower hypocretin-1 concentrations. No significant differences were found between clusters 5 and 6 on MSLT-related variables and the Epworth Sleepiness Scale. Cluster 7 is a smaller cluster evenly mixing individuals with and without cataplexy. Apart from the presence of hypnagogic hallucinations and sleep paralysis, there are no clear distinguishing variables from other clusters. 9
RkJQdWJsaXNoZXIy MjY0ODMw