Thesis

204 Chapter 7 Behavioural effect Behavioural analyses are visualized in Figure 2. For a complete overview of behavioural SART analyses, see Appendix A. Two-way ANOVA showed a significant main effect for the difficulty level (F(1,21) = 9.04, p = 0.007), such that the average error score over all participants was significantly larger in the higher than the moderate difficulty level (Figure 2A). When splitting the groups, people with narcolepsy type 1—but not controls— made significantly more mistakes upon increasing difficulty (t(11) = −3.07, p = 0.011). Reaction times were numerically, but not significantly, longer in people with narcolepsy type 1 than in controls over the two difficulty levels (F(1,21) = 4.05, p = 0.057) (Figure 2B). Over repetitions, significantly more mistakes were made in repetition 4 than repetition 1 in the moderate difficulty level (F(1,21) = 11.88, p = 0.002), but not the higher difficulty level (Figure 2C). This increase in error scores in the moderate difficulty level was not significantly different between participant groups. No significant main effects on reaction time were found in the timeon-task analyses over repetitions (Figure 2D). The time-on-task within blocks analysis showed that more mistakes were made in the late half compared to the early half of the blocks of the higher difficulty level when combining all participants (F(1,21) = 25.37, p < 0.001) (Figure 2E). This increase in errors in the higher difficulty level did not significantly differ between people with narcolepsy type 1 and controls (F(1,21) = 2.32, p = 0.143). No significant main effect of block half was found on mean error rates in the moderate difficulty level after correction for multiple comparisons (F(1,21) = 4.98, p = 0.037) or on the mean reaction times in both difficulty levels (Figure 2F).

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