192 Chapter 6 Supplementary Table 5: Continued. Staining Region Narcolepsy type 1 Mean (SD) Controls Mean (SD) p-value q-value Effect size Myelin integrity (PLP colour intensity) Reticular formation (RF) 0.63 (0.09) 0.66 (0.06) 0.565 0.998 0.39 Pyramidal tract (P)† 0.68 (0.18) 0.68 (0.04) 0.975 0.998 0.03 Proximal corpus callosum (P-CC) 0.65 (0.11) 0.73 (0.06) 0.218 0.491 0.87 Distal corpus callosum (D-CC) 0.71 (0.05) 0.73 (0.11) 0.800 0.998 0.17 Anterior cingulate gyrus (ACC) 0.71 (0.09) 0.71 (0.10) 0.998 0.998 0.00 Cingulate sulcus (CS) 0.72 (0.07) 0.73 (0.09) 0.799 0.998 0.17 Primary visual cortex (V1) 0.80 (0.04) 0.72 (0.06) 0.095 0.285 1.26 Secondary visual cortex (V2) 0.73 (0.02) 0.81 (0.02) 0.004 0.036 2.83 Vermis (CB)† 0.70 (0.02) 0.61 (0.09) 0.074 0.285 1.13 Overview of means and standard deviations of the colour intensity (Bielschowsky, LFB, PLP) and area percentage stained (SMI312) analyses. q-values correspond to significance levels after the Benjamini–Hochberg procedure to decrease the false discovery rate to 0.05. q-values below 0.05 are made bold. † Welch’s t-tests were performed. # Wilcoxon-Mann-Whitney U test was performed.
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