191 Axonal Loss in Narcolepsy Type 1 Supplementary Table 5: Continued. Staining Region Narcolepsy type 1 Mean (SD) Controls Mean (SD) p-value q-value Effect size Axonal injury (SMI312 area percentage stained) Reticular formation (RF) 24.44 (3.13) 23.23 (1.97) 0.518 0.932 0.44 Pyramidal tract (P) 26.02 (2.36) 24.47 (0.98) 0.230 0.932 0.85 Proximal corpus callosum (P-CC) 20.80 (2.97) 23.00 (4.20) 0.463 0.932 0.50 Distal corpus callosum (D-CC) 22.40 (2.82) 22.33 (2.77) 0.976 0.995 0.02 Anterior cingulate gyrus (ACC)† 18.56 (5.31) 20.29 (1.94) 0.634 0.951 0.44 Cingulate sulcus (CS) 20.60 (2.73) 20.56 (4.09) 0.990 0.995 0.01 Primary visual cortex (V1) 21.74 (1.65) 20.54 (2.67) 0.516 0.932 0.44 Secondary visual cortex (V2) 21.19 (2.09) 21.20 (2.62) 0.995 0.995 0.00 Vermis (CB) 26.89 (0.25) 23.73 (2.96) 0.124 0.932 1.14 Myelin integrity (LFB colour intensity) Reticular formation (RF) 0.52 (0.09) 0.58 (0.06) 0.258 0.581 0.79 Pyramidal tract (P) 0.76 (0.03) 0.74 (0.05) 0.609 0.766 0.34 Proximal corpus callosum (P-CC) 0.85 (0.07) 0.93 (0.05) 0.091 0.410 1.28 Distal corpus callosum (D-CC) 0.83 (0.09) 0.85 (0.05) 0.652 0.766 0.30 Anterior cingulate gyrus (ACC) 0.75 (0.07) 0.71 (0.14) 0.681 0.766 0.28 Cingulate sulcus (CS) # 0.84 (0.04) 0.74 (0.20) 0.655 0.766 0.16 Primary visual cortex (V1) 0.85 (0.04) 0.78 (0.07) 0.198 0.581 0.92 Secondary visual cortex (V2) 0.82 (0.05) 0.82 (0.10) 0.859 0.859 0.12 Vermis (CB)† 0.85 (0.05) 0.69 (0.14) 0.064 0.410 1.18 6
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