Thesis

185 Axonal Loss in Narcolepsy Type 1 Supplementary Figure 1. Example of the SMI312 axonal integrity pixel classifier. (A) Distal corpus callosum ROI as an example input for the SMI312 pixel classifier script. (B) Zoomed version of A (black box) that displays the neurofilament medium and heavy chains prior to classification. (C) Same distal corpus callosum ROI as in A with in red the neurofilament medium and heavy chains coloured. (D) Zoomed version of C (black box) that displays the neurofilament medium and heavy chains in red. The scale bars represent 250 µm for A and C, and 50 µm for B and D. 6

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