Thesis

172 Chapter 6 Table 2: Continued. Donor ID Sex Age (year) PMD (year) Disease duration (year) CSF-pH Brain weight (gram) HCRT cells (count) Braak NFT stage Amyloid stage Braak LB stage Cause of death Relevant medication Control midbrain 5 Male 86 6.8 N/A 6.4 1,340 N/A 3 O 0 Intra-abdominal fluid leakage causing abdominal infection - Amyloid stages O-A-B-C represent increasing presence of amyloid depositions (PMID: 1759558). Braak NFT stage = Braak neurofibrillary tangle stages (PMID: 16906426); Braak LB = Braak stages for Lewy bodies (PMID: 12498954); HCRT = hypocretin; NT1 = Narcolepsy type 1; N/A = not available; PMD = postmortem delay.

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