146 Chapter 5 Table 4: Hypothalamic white matter connectivity Fractional anisotropy Mean diffusivity Tract volume* Patients Controls P-value Patients Controls P-value Patients Controls P-value Left – left thalamus 0.411 (0.033) 0.426 (0.022) 0.229 0.900 (0.085) 0.842 (0.075) 0.127 1.909 (0.753) 1.897 (0.760) 0.991 Right – right thalamus 0.412 (0.038) 0.430 (0.027) 0.191 0.918 (0.078) 0.911 (0.074) 0.814 2.017 (1.148) 2.052 (1.044) 0.745 Left – left amygdala 0.426 (0.050) 0.438 (0.045) 0.319 0.846 (0.115) 0.796 (0.058) 0.222 0.773 (0.324) 0.799 (0.392) 0.850 Right – right amygdala 0.399 (0.053) 0.418 (0.044) 0.239 0.940 (0.138) 0.849 (0.064) 0.058 0.782 (0.305) 0.873 (0.461) 0.560 Left – midbrain 0.419 (0.031) 0.458 (0.030) 0.007 0.782 (0.108) 0.758 (0.085) 0.512 2.156 (0.912) 2.894 (0.890) 0.034 Right - midbrain 0.405 (0.035) 0.428 (0.041) 0.130 0.868 (0.134) 0.861 (0.062) 0.845 2.395 (1.540) 3.595 (1.468) 0.079 Each row represents the tracts connecting the left or right hypothalamus with the mentioned region-of-interest. Values are reported as mean (standard deviation). * Tract volume is in cm3.
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