142 Chapter 5 Figure 2. The averaged FA map masked with the JHU tractography atlas labels (red-yellow). Reported as absolute significantly different voxel count within the label/total voxels within the label, corresponding percentage of significant voxels, minimum p-value found within the label. Region-of-interest analyses (II) As expected from the TBSS results, statistically significant lower FA was seen in patients (Table 2, Figure 3) in the ventral diencephalon [left: F(1,19) = 16,024, p = .001; right: F(1,19) = 6.604, p = .019], left thalamus [F(1,19) = 5.365, p = .032] and midbrain [F(1,19) = 4.394, p = .050]. Patients also showed higher MD in the left ventral diencephalon [F(1,19) = 5.511, p = .030]. After Bonferroni correction for multiple comparisons (p < .0029) only the lower FA in the left ventral diencephalon maintained its significance. Post-hoc analyses on the bilateral ventral diencephalon, left thalamus and midbrain (Table 3) found significantly lower AD in the midbrain [F(1,19) = 10.934, p = .004] and significantly higher RD in the left ventral diencephalon [F(1,19) = 8.722, p = .008] in patients.
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