Thesis

102 Chapter 4 comparisons between subgroups but both diagnoses contributed similarly to the reported infections and influenza vaccinations. Figure 2. Immunological events overview for narcolepsy type 2 and idiopathic hypersomnia. If no exact timing of the immunological event was known, this individual was not included in column 3. EBV = Epstein–Barr virus; IH = idiopathic hypersomnia; NT2 = narcolepsy type 2. Infection history An infection before onset of narcolepsy type 2 or idiopathic hypersomnia was reported in 28/44 (63.6%; Figure 2A). EBV was reported most (10/44, 22.7% of total sample), followed by other respiratory infections (8/44, 18.2% of total sample), other non-respiratory infections (8/44, 18.2% of total sample) and flu (2/44, 4.5% of total sample). Other respiratory infections reported included pharyngitis (N = 2), allergic rhinitis (N = 1), allergic bronchitis (N = 1), pneumonia (N = 1), cmv (N = 1), scarlet fever with fever, sore throat, skin rash and secondary pyelonephritis (N = 1) and (unspecified) pulmonary infection (N = 1). Nonrespiratory infections included fever of unknown origin (N = 2), appendicitis (N = 2), cholecystitis (N = 1), pyelonephritis (N = 1), meningitis (N = 1) and otitis (N = 1). Onset of narcolepsy type 2 or idiopathic hypersomnia within one year

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