Table of contents Chapter 1 General introduction 7 Chapter 2 Covid-19 reveals influence of physical activity on symptom severity in Hereditary Spastic Paraplegia Journal of Neurology. 2020 Dec;267(12):3462-3464. 21 Chapter 3 Improving gait adaptability in patients with Hereditary Spastic Paraplegia (Move-HSP): study protocol for a randomized clinical trial Trials. 2021 Jan 7;22(1):32 29 Chapter 4 Gait-adaptability training in Hereditary Spastic Paraplegia: a randomized clinical trial Neurorehabilitation and Neural Repair, 2023 Jan;37(1):27-36 49 Chapter 5 Increased trunk movements in people with hereditary spastic paraplegia: do these involve balance correcting strategies? Journal of Neurology. 2022 Aug;269(8):4264-4269 69 Chapter 6 Are clinical tests and biomechanical gait stability measures able to identify fallers in hereditary spastic paraplegia? Submitted 83 Chapter 7 Summary and general discussion 101 Chapter 8 Samenvatting 123 Appendices Dankwoord Curriculum Vitae List of Publications Portfolio Research data management according to FAIR principles Donders Graduate School for Cognitive Neuroscience 133 141 143 145 148 151
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