Low methylation levels among HPV-vaccinated women with cervical HSIL 153 7 HPV-vaccinated cervical lesions Controls (n = 371) LSIL (n = 15) HSIL (n = 17) HPV68 8 (2.2%) - - HPV70 5 (1.4%)‡ 2 (13.3%)‡ 1 (5.9%) HPV73* 4 (1.1%) - - HPV82 1 (0.3%) - - Group 3 - Not carcinogenic HPV6 8 (2.2%) - 2 (11.8%) HPV11 2 (0.5%) 1 (6.7%) - HPV40 4 (1.1%) - - HPV42 10 (2.7%) - - HPV43 - 1 (6.7%) - HPV61 7 (1.9%) - 1 (5.9%) HPV74 8 (2.2%) - - HPV81 6 (1.6%) - - HPV83 2 (0.5%) - - HPV86 1 (0.3%) - - HPV87 9 (2.4%) 1 (6.7%) 1 (5.9%) HPV89 12 (3.2%) 1 (6.7%) - HPV90 17 (4.6%) 1 (6.7%) - HPV91 3 (0.8%) - - †‡ Comparisons in bold, p value < 0.05; ^Part of single or multiple infection, classification according to IARC; those HPV genotypes that were negative in all groups are not shown (Group 1: HPV18 and HPV31; Group 2a/2b: HPV26, HPV34, HPV69, HPV85 and HPV97; and Group 3: HPV54, HPV62, HPV71 and HPV72). Abbreviations: LSIL, low-grade intraepithelial lesion; HSIL, high-grade intraepithelial lesion: HR, highrisk: LR, low-risk; HPV, human papillomavirus; SD, standard deviation; n, number of
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