91 Tau PET and cognition Table 3. Regional association between [18F]flortaucipir BP ND (rows) and R1 (columns). [18F]flortaucipir R 1 Medial temporal Lateral temporal Parietal Occipital Frontal [18F]flortaucipir BP ND Medial temporal -0.10 [-0.32 − 0.13] -0.21 [-0.44 -0.02] -0.11 [-0.35 − 0.13] 0.03 [-0.21 − 0.27] -0.18 [-0.41− 0.05] Lateral temporal -0.15 [-0.38 − 0.08] -0.32*‡ [-0.56 − -0.08] -0.24 [-0.49 − 0.01] -0.10 [-0.35 − 0.16] -0.19 [-0.43 − 0.06] Parietal 0.10 [-0.18 − 0.38] -0.14 [-0.44 − 0.16] -0.43*‡ [-0.72 − -0.14] -0.29 [-0.59 − 0.00] 0.04 [-0.26 − 0.33] Occipital 0.02 [-0.24 − 0.27] -0.07 [-0.34 − 0.20] -0.38*‡ [-0.64 − -0.12] -0.53†‡ [-0.78 − -0.29] 0.13 [-0.13 − 0.40] Frontal 0.12 [-0.12 − 0.36] -0.18 [-0.43 − 0.08] -0.23 [-0.49 − 0.03] 0.09 [-0.18 − 0.35] -0.14 [-0.40 − 0.11] Model is adjusted for age and sex. Standardized β’s with 95% confidence intervals are reported. BPND = non-displaceable binding potential. *p<0.01, †p<0.001, ‡p FDR<0.05. 4
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