70 Chapter 3 Supplementary Table 4. Percentage overestimation of SUVr80-100 relative to DVR. Mean ± SD are provided. SCD = subjective cognitive decline. AD = Alzheimer’s disease. DVR = distribution volume ratio ( = binding potential (BPND) + 1 ). SUVr = standardized uptake value ratio. SCD AD BL FU BL FU Braak I/II 8.95 (3.92) 8.16 (3.39) 11.49 (3.46) 11.18 (3.21) Braak III/IV 5.34 (3.02) 4.97 (2.67) 8.59 (3.04) 9.47 (3.29) Braak V/VI 3.19 (2.35) 3.00 (1.98) 7.08 (3.59) 7.97 (3.47) Supplementary Table 5. Annualized %change for 18F-flortaucipir DVR and SUVr 80100 in SCD subjects. Mean ± SD are provided. SCD = subjective cognitive decline. AD = Alzheimer’s disease. DVR = distribution volume ratio ( = binding potential (BPND) + 1 ). SUVr = standardized uptake value ratio. SCD (n=38) Annualized %change DVR Annualized %change SUVr80-100 Braak I/II 1.27 (1.44) 0.92 (1.62) Braak III/IV 1.41 (1.31) 1.23 (1.32) Braak V/VI 1.16 (1.38) 1.08 (1.61) Supplementary Table 6. Annualized %change for 18F-flortaucipir DVR and SUVr 80-100 values in AD patients. Mean ± SD are provided. SCD = subjective cognitive decline. AD = Alzheimer’s disease. DVR = distribution volume ratio ( = binding potential (BPND) + 1 ). SUVr = standardized uptake value ratio. AD (n=24) Annualized %change DVR Annualized %change SUVr80-100 Braak I/II 1.54 (1.77) 1.42 (2.35) Braak III/IV 2.86 (2.13) 3.23 (2.51) Braak V/VI 3.15 (2.65) 3.53 (3.01)
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