Thesis

The research described in this thesis was carried out at the department of Radiology & Nuclear Medicine and Alzheimer Center Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands. Research of the Alzheimer Center is part of the Neurodegeneration program of Amsterdam Neuroscience. The Alzheimer Center is supported by Stichting Alzheimer Nederland and Stichting Steun Alzheimercentrum Amsterdam. Tau-PET research in this thesis was made possible by Avid Radiopharmaceuticals, ZonMW Memorabel and Stichting Alzheimer Nederland. Printing of this thesis was supported by Stichting Alzheimer Nederland, Stichting Alzheimer en Neuropsychiatrie and Vrije Universiteit Amsterdam. Cover concept: Leo & Denise Visser Cover design: Designed by Loniek Layout: Bart Roelofs, persoonlijkproefschrift.nl Printed by Ipskamp Printing | proefschriften.net ISBN: 978-94-6473-321-1 © 2023 Denise Visser All rights reserved. Save expectations stated by law, no part of this thesis may be reproduced stored in a retrieval system of any nature, or transmitted, in whole or in part, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, included in a complete or partial transcription, without the written permission of the author, or- when appropriate – of the publisher’s of the presented publications.

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