35 Shortening the scan duration Table 3. Comparison of RPM BPND obtained with the shortest scanning interval (0-30/80-100) and SUVr(80-100min) to plasma-input DVR-1, SRTM BPND and RPM BPND derived from the original scan duration (0-60/80-130). DVR-1 (0-60/80-130) SRTM BPND (0-60/80-130) RPM BPND (0-60/80-130) HC AD HC AD HC AD r2 Slope r2 Slope r2 Slope r2 Slope r2 Slope r2 Slope POP-IP 2T4k_VB RPM BPND (0-30/80-100) 0.94 0.94 0.95 0.93 0.98 1.04 0.97 0.84 0.98 1.03 0.99 0.95 Cubic RPM BPND (0-30/80-100) 0.94 0.93 0.94 0.90 0.98 1.03 0.97 0.81 0.98 1.02 0.99 0.92 SUVr (80-100) 0.80 0.95 0.92 1.10 0.90 1.15 0.93 0.98 0.87 1.11 0.96 1.13 The correlation and slope for the original scan duration between RPM BPND and DVR-1 was r2= 0.95 slope= 0.91 for HC and, r2= 0.96 slope= 0.98 for AD. The correspondence between original RPM BPND and SRTM BPND was r2= 1.00 slope= 1.01 for HC and r2= 0.98 slope= 0.88 for AD. 2
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