Thesis

225 Longitudinal change in ATN biomarkers 29. Guo T, Shaw LM, Trojanowski JQ, Jagust WJ, Landau SM. Alzheimer’s disease neuroimaging I. association of CSF Aβ, amyloid PET, and cognition in cognitively unimpaired elderly adults. Neurology. 2020;95(15):e2075–e85. 30. Koychev I, Vaci N, Bilgel M, An Y, Muniz GT, Wong DF, et al. Prediction of rapid amyloid and phosphorylated-tau accumulation in cognitively healthy individuals. Alzheimer’s Dement (Amsterdam, Netherlands). 2020;12(1):e12019. 31. Toledo JB, Habes M, Sotiras A, Bjerke M, Fan Y, Weiner MW, et al. APOE effect on amyloid-β PET spatial distribution, deposition rate, and cutpoints. J Alzheimer’s Dis. 2019;69(3):783– 93. 32. Whitwell JL, Tosakulwong N, Weigand SD, Graff-Radford J, Duffy JR, Clark HM, et al. Longitudinal amyloid-β PET in atypical Alzheimer’s disease and frontotemporal lobar degeneration. J Alzheimer’s Dis. 2020;74(1):377–89. 33. Hatashita S, Wakebe D, Kikuchi Y, Ichijo A. Longitudinal assessment of amyloid-β deposition by [18F]-flutemetamol PET imaging compared with [11C]-PIB across the spectrum of Alzheimer’s disease. Front Aging Neurosci. 2019;11:251. 34. Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Knopman DS, Lowe V, et al. Age-specific and sex-specific prevalence of cerebral beta-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50-95 years: a cross-sectional study. Lancet Neurol. 2017;16(6):435–44. 35. Ingala S, De Boer C, Masselink LA, Vergari I, Lorenzini L, Blennow K, et al. Application of the ATN classification scheme in a population without dementia: findings from the EPAD cohort. Alzheimer’s Dement. 2021;17(7):1189–204. 36. Eckerström C, Svensson J, Kettunen P, Jonsson M, Eckerström M. Evaluation of the ATN model in a longitudinal memory clinic sample with different underlying disorders. Alzheimer’s Dement (Amsterdam, Netherlands). 2021;13(1):e12031-e. 37. Marquié M, Verwer EE, Meltzer AC, Kim SJW, Agüero C, Gonzalez J, et al. Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson’s case. Acta neuropathologica communications. 2017;5(1):75. 8

RkJQdWJsaXNoZXIy MjY0ODMw