202 Chapter 7 Supplementary Figure 4. Association between annual change in tau PET (BPND/year) and longitudinal R1 in a) amyloid negative and b) amyloid positive individuals. Forest plot showing model estimates with 95% confidence intervals from linear mixed models with annual change in tau PET BPND as determinant, longitudinal rCBF (R1) as outcome measure and age, sex, time, and baseline R1 as covariates. Grey = non-significant. Blue = puncorrected<0.05. Red = pFDR<0.05.
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