171 Longitudinal tau PET and cognition Supplementary Figure 9. Associations between baseline (BL) tau PET BPND with cognitive test scores (over time) while adjusting for R1 using only cognitive data from the baseline PET scan onward. Model coefficients with 95% confidence intervals from linear mixed models with baseline tau PET BPND (per ROI) and R1 as determinant, longitudinal cognitive test score (scaled) as outcome, adjusted for age-at-PET, sex and education. Cross-sectional results represent the coefficient for “baseline tau PET BPND (per ROI)” and longitudinal results represent the coefficient for “baseline tau PET BPND (per ROI) x time”. Red = PFDR<0.05. Blue = P<0.05. Grey = P≥0.05. 6
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