Thesis

149 Longitudinal tau PET and cognition Figure 1. Associations between baseline (BL) tau PET BPND with cognitive test scores at baseline and over time. Model coefficients with 95% confidence intervals from linear mixed models with baseline tau PET BPND (per ROI) as determinant, longitudinal cognitive test score (scaled) as outcome, adjusted for age-at-PET, sex and education. Cross-sectional results represent the coefficient for “baseline tau PET BPND (per ROI)” and longitudinal results represent the coefficient for “baseline tau PET BPND (per ROI) x time”. Red = PFDR<0.05. Blue = P<0.05. Grey = P≥0.05. 6

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