134 Chapter 5 Supplementary Figure 4. Partial volume-corrected (PVC) [18F]flortaucipir BP ND for early- and late-onset AD. a) Boxplot of partial volume-corrected [18F]flortaucipir BP ND values for each region-of-interest (ROI). Differences were assessed using ANOVA, adjusted for sex. b-f) Scatterplots for partial volume-corrected [18F]flortaucipir BP ND by age for each ROI. g) Results from voxel-wise contrast for partial volume-corrected [18F]flortaucipir BP ND between early-onset AD (EOAD) and late-onset AD (LOAD). Indicated by the black lines on the color scale are thresholds for p<0.001, uncorrected (t = 3.20) and for p<0.05, FWE-corrected (t = 5.24). *p<0.05, **p<0.01, ***p<0.001, †pFDR<0.05.
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