121 Tau PET and cognition in early- and late onset AD Figure 4. Associations between [18F]flortaucipir BP ND and cognitive test scores for early- and late-onset AD. a) Significant modification of age-at-onset as assessed in the model including all AD subjects from the cognition subsample (n=72), adjusted for age, sex, and education is depicted in grey (representing interaction terms at p≤0.10) and black (representing interaction terms at pFDR≤0.05) squares. Standardized regression coefficients are depicted for early-onset AD (EOAD) and late-onset AD (LOAD) separately. b) A selection of scatterplots for the association between [18F]flortaucipir BP ND and neuropsychological test scores. 5
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