102 Chapter 4 SUPPLEMENTARY MATERIAL Supplementary Table 1. Regional association between [18F]flortaucipir BP ND (rows) and R1 (columns), corrected for Fazekas score. [18F]flortaucipir R 1 Medial temporal Lateral temporal Parietal Occipital Frontal [18F]flortaucipir BP ND Medial temporal -0.10 [-0.32 – 0.13] -0.20 [-0.44 – 0.04] -0.09 [-0.34 – 0.15] 0.06 [-0.19 – 0.30] -0.16 [-0.40 – 0.08] Lateral temporal -0.15 [-0.39 – 0.09] -0.31* [-0.56 − -0.07] -0.23 [-0.48 – 0.03] -0.07 [-0.33 – 0.19] -0.17 [-0.42 - 0.08] Parietal 0.11 [-0.18 – 0.39] -0.13 [-0.43 – 0.17] -0.42†§ [-0.71 − -0.13] -0.28 [-0.57 – 0.02] 0.05 [-0.24 – 0.35] Occipital 0.02 [-0.24 – 0.27] -0.07 [-0.34 – 0.21] -0.38†§ [-0.64 − -0.12] -0.53‡§ [-0.78 − -0.29] 0.14 [-0.13 – 0.40] Frontal 0.13 [-0.11 – 0.38] -0.16 [-0.42 – 0.10] -0.22 [-0.48 – 0.05] 0.11 [-0.15 – 0.38] -0.12 [-0.38 - 0.13] Model is adjusted for age, sex and Fazekas score. Standardized β’s with 95% confidence intervals are reported. BPND = non-displaceable binding potential. p<0.05, †p<0.01, ‡p<0.001, §p FDR<0.05.
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