Thesis

90 Chapter 4 Supplementary table 3. Quality of the evidence of analyses on the effect of DBS on refractory-treatment AN patients Analysis Study design Risk of bias Inconsistency Indirectness Imprecision Publication bias Effect size Final GRADE score BMI +3, nonRCTs -1 0, no heterogeneity 0 0 0, undetected +1 ⊕⊕⊕⊝ moderate Psychiatric symptoms +3, nonRCTs -2 0, no heterogeneity 0 0 0, undetected +1 ⊕⊕⊝⊝ low Supplementary figure 1a. Risk of bias of objective measurements of included studies (BMI) Supplementary figure 1b. Risk of bias of subjective measurements of included studies (psychiatric symptom severity)

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