60 Chapter 3 Supplement 1. Adverse events and their relation to the intervention. Related to DBS Event Times reported n DBSAN-001 DBSAN-002 DBSAN-003 DBSAN-004 Probable (3) Hypomanic symptoms 3 3 1 1 1 Possible (34) Auto-intoxication 19 3 10 3 6 Self-destructive behavior 6 2 3 3 Aggressive behavior 1 1 1 Alcohol consumption 1 1 1 Water intoxication 2 2 1 1 Migraine 4 1 4 Pain at battery site 1 1 1 Unlikely (36) Compromised somatic condition related to malnutrition (hypokalemia; hypoglycemia; hypothermia; hyponatremia)² 18 2 11 7 Low consciousness 2 1 2 Edema 3 2 2 1 Low vitamin D 2 2 1 1 Urinary tract infection 1 1 1 Pneumonia 2 1 2 High anti-TPO 1 1 1 Shoplifting 3 2 2 1 Pain lower legs 1 1 1 Ear infection 1 1 1 Pain legs/back 1 1 1 Cannabis usage 1 1 1 Total number AE’s 73 37 21 13 2
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