112 Chapter 5 a. Right precuneus b. Right ventral striatum Figure 5. Significant interaction effects for loss anticipation for each anatomical region displayed at p<0.001, uncorrected (left) and corresponding bar plots displaying the contrast estimates for the interactions at the peak voxels (right). Table 3. Significant interaction effects for loss anticipation, pre- and post-DBS are compared for AN versus HC. The direction of the effect is illustrated by an increase or decrease for the AN group post-DBS. Anatomical region Time point Effect ↑ increase ↓ decrease Cluster size MNI-coordinates Statistics x y z Z-score p-value Precuneus R. Post-DBS AN ↓ 222 10 -44 64 4.15 0.007 VS R. Post-DBS AN ↓ 91 12 -4 -4 3.89 0.012* * p-value after small volume correction (SVC)
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