186 Chapter 7 Day 1 Day 2 morning afternoon evening morning afternoon evening 0 1 2 3 4 5 Methylation level (sqrt ct ratio) CDO1 a Day 1 Day 2 morning afternoon evening morning afternoon evening 0 1 2 3 4 Methylation level (sqrt ct ratio) SOX17 b Day 1 Day 2 morning afternoon evening morning afternoon evening 0 1 2 3 4 Methylation level (sqrt ct ratio) TAC1 c Figure 3: Methylation levels of CDO1 (a), SOX17 (b), and TAC1 (c) measured in the urine of NSCLC patients at different collection time points illustrating the median and IQR of each collection moment. Methylation levels are normalized according to the reference gene ACTB and presented as square root Ct ratios. No significant differences were found within or between the days. IQR = interquartile range; NSCLC = non-small cell lung cancer.
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