172 Chapter 6 Stage 1a 1b 1c 2a 2b 3a 3b N - 12 15 1 1 2 3 0 N + 0 0 0 0 1 5 4 N- N+ 0 1 2 3 .258 5 N- N+ .034 N- N+ .863 CDO1 SOX17 TAC1 Methylation level (sqrt Ct ratio) Supplementary Figure 3: Methylation levels of NSCLC patients without (N-) and with (N+) lymph node involvement. Methylation levels of markers CDO1, SOX17, and TAC1 in the urine supernatant of surgical NSCLC patients, stratified by nodal involvement. Data is depicted as the median with an interquartile range of square root transformed Ct ratios. Each symbol represents a single case. The distribution of nodal involvement per stage is depicted underneath. A P-value of <.05 was considered statistically significant. LUAD = lung adenocarcinoma, LUSC = lung squamous cell carcinoma, NOS = carcinoma not otherwise specified.
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