138 Chapter 5 p = 0.0031 0.001024 0.138 −10 −5 0 5 10 C2CD4D p = 0.012 0.004 0.154 CDO1 p = 0.16 GALR1 p = 0.23 −10 −5 0 5 10 GHSR p = 0.53 MAL p = 0.7 NRN1 p = 0.3 −10 −5 0 5 10 PRDM14 p = 0.33 SST p = 0.47 ZIC1 diagnosis Control Benign Malignant Clinician−taken cervical scrape DNA methylation level (2log transformed Cq value) Supplemental Figure 5: DNA methylation levels of C2CD4D, CDO1, GALR1, GHSR, MAL, NRN1, PRDM14, SST, and ZIC1 in clinician-taken cervical scrapes of healthy controls (n=40), and women diagnosed with a benign (n=23) or high-stage malignant ovarian mass (n=24). DNA methylation levels are shown by 2log-transformed Cq ratios. Violin plots represent medians with lower and upper quartile and range whiskers. A p-value of <0.05 was considered statistically significant. Cq = quantification cycle.
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