136 Chapter 5 p = 0.076 −10 −5 0 5 10 C2CD4D p = 0.48 −10 −5 0 5 10 CDO1 p = 0.23 −10 −5 0 5 10 GALR1 p = 0.086 −10 −5 0 5 10 GHSR p = 0.0023 0.001088 0.264 −10 −5 0 5 10 MAL p = 0.57 −10 −5 0 5 10 NRN1 p = 3.4e−05 0.00033 1 −10 −5 0 5 10 PRDM14 p = 0.12 −10 −5 0 5 10 SST p = 0.63 −10 −5 0 5 10 ZIC1 diagnosis Control Benign Malignant Urine supernatant DNA methylation level (2log transformed Cq value) Supplemental Figure 3: DNA methylation levels of C2CD4D, CDO1, GALR1, GHSR, MAL, NRN1, PRDM14, SST, and ZIC1 in urine supernatant of healthy controls (n=29), and women diagnosed with a benign (n=27) or high-stage malignant ovarian mass (n=29). DNA methylation levels are shown by 2log-transformed Cq ratios. Violin plots represent medians with lower and upper quartile and range whiskers. A p-value of <0.05 was considered statistically significant. Cq = quantification cycle.
RkJQdWJsaXNoZXIy MjY0ODMw