134 Chapter 5 **** −10 −5 0 5 10 15 C2CD4D **** −10 −5 0 5 10 15 CDO1 **** −10 −5 0 5 10 15 GALR1 **** −10 −5 0 5 10 15 GHSR **** −10 −5 0 5 10 15 MAL **** −10 −5 0 5 10 15 NRN1 **** −10 −5 0 5 10 15 PRDM14 **** −10 −5 0 5 10 15 SST **** −10 −5 0 5 10 15 ZIC1 diagnosis normal fallopian tube HGSOC Tissue DNA methylation level (2log transformed Cq value) Supplemental Figure 1: DNA methylation levels of C2CD4D, CDO1, GALR1, GHSR, MAL, NRN1, PRDM14, SST, and ZIC1 in high-grade serous ovarian cancer (n=35) and normal fallopian tube tissue (n=22). DNA methylation levels are shown by 2log-transformed Cq ratios. Violin plots represent medians with lower and upper quartile and range whiskers. A p-value of <0.05 was considered statistically significant. ****: p < 0.0001. Cq = quantification cycle; HGSOC = high-grade serous ovarian cancer.
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