97 Comparison of MRI response evaluation methods in rectal cancer: a multicentre and multireader validation study 6 Figure 3 Impact of reader experience. Pre-treatment axial T2-weighted (A) and post-CRT axial T2-weighted (B) and DWI (C) images of a male patient with a scan graded as good quality. On pre-treatment MRI, a circular tumour lesion is seen. Post-CRT, predominant tumour signal remains with persistent high signal on DWI. As detailed in the boxes below the images, the expert readers reached 80-100% agreement for the different scoring methods; for the less-experienced general and abdominal radiologists, agreement for the different scoring methods was much lower, ranging from 29-76%.
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