5 Contents Chapter 1 Introduction, aims and outline of the thesis 7 Chapter 2 El Khababi et al. “Pearls and pitfalls of structured staging and 15 reporting of rectal cancer on MRI: an international multireader study” Published in BJR 2023; 96(1150):20230091 Chapter 3 El Khababi et al. “Outcomes and potential impact of a virtual hands-on 35 training program on MRI staging confidence and performance in rectal cancer ” Published in Eur Radiol 2023 (ePub ahead of print) Chapter 4 Bogveradze, El Khababi et al. “Evolutions in rectal cancer MRI staging 53 and risk stratification in the Netherlands” Published in Abdom Radiol (NY) 2022; 47:38-47 Chapter 5 El Khababi et al. “Sense and nonsense of yT-staging on MRI after 69 chemoradiotherapy in rectal cancer.” Published in Colorectal Disease 2023; 25(9):1878-1887 Chapter 6 El Khababi et al. “Comparison of MRI response evaluation methods 85 in rectal cancer: a multicentre and multireader validation study Published in Eur Radiol 2023; 33(6):4367-4377 Chapter 7 El Khababi et al. “Predicting response to chemoradiotherapy in 115 rectal cancer via visual assessment on baseline staging MRI: a multicentre and multireader study Published in Abdom Radiol (NY) 2023; 48(10):3039-3049 Chapter 8 General Discussion 141 Appendices Summary 152 Samenvatting 154 Scientific impact 157 List of publications 160 Dankwoord 162 Curriculum Vitea 164
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