133 Predicting response to chemoradiotherapy in rectal cancer via visual morphologic assessment and staging on baseline MRI 7 31. Smolskas E, Mikulskytė G, Sileika E, Suziedelis K, Dulskas A (2022) Tissue-Based Markers as a Tool to Assess Response to Neoadjuvant Radiotherapy in Rectal Cancer-Systematic Review. Int J Mol Sci 23(11):6040. https://doi.org/10.3390/ijms23116040 32. Lee HH, Chen CH, Huang YH, Chiang CH, Huang MY (2022) Biomarkers of Favorable vs. Unfavorable Responses in Locally Advanced Rectal Cancer Patients Receiving Neoadjuvant Concurrent Chemoradiotherapy. Cells 11(10):1611. https://doi.org/10.3390/cells11101611 33. Dizdarevic E, Hansen TF, Jakobsen A (2022) The Prognostic Importance of ctDNA in Rectal Cancer: A Critical Reappraisal. Cancers (Basel) 14(9):2252. https://doi.org/10.3390/cancers14092252 34. Sloothaak DA, Geijsen DE, van Leersum NJ et al (2013) Optimal time interval between neoadjuvant chemoradiotherapy and surgery for rectal cancer. Br J Surg 100(7):933-939. https://doi.org/10.1002/bjs.9112 35. Probst CP, Becerra AZ, Aquina CT et al (2015) Extended Intervals after Neoadjuvant Therapy in Locally Advanced Rectal Cancer: The Key to Improved Tumor Response and Potential Organ Preservation. J Am Coll Surg 221(2):430-440. https://doi.org/10.1016/j.jamcollsurg.2015.04.010 36. Petrelli F, Sgroi G, Sarti E, Barni S (2016) Increasing the Interval Between Neoadjuvant Chemoradiotherapy and Surgery in Rectal Cancer: A Meta-analysis of Published Studies. Ann Surg 263(3):458-464. https://doi.org/10.1097/SLA.0000000000000368 37. Du D, Su Z, Wang D, Liu W, Wei Z (2018) Optimal Interval to Surgery After Neoadjuvant Chemoradiotherapy in Rectal Cancer: A Systematic Review and Meta-analysis. Clin Colorectal Cancer 17(1):13-24. https://doi.org/10.1016/j.clcc.2017.10.012 38. Awawda M, Taha T, Salman S, Billan S, Hijab A (2022) The evolving treatment paradigm of locally advanced rectal cancer: a narrative review. J Gastrointest Oncol 13(4):2033-2047. https://doi. org/10.21037/jgo-22-13
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