Prognostic factors of adherence 71 Therapy-related factors Therapy-related prognostic factors reported in more than one study included only duration of rehabilitation. However, this prognostic factor was not predictive of exercise adherence. Condition-related factors Condition-related prognostic factors reported in more than one study included BMI, comorbidities, depression and fatigue. The condition-related factors to be predictive of exercise adherence were less comorbidities, less depressive symptoms and less fatigue. Moderate-quality evidence suggested that higher exercise adherence was predicted by having less comorbidities, less depressive symptoms and being less fatigued. The pooled ORs showed a significant better adherence rate; comorbidities OR = 0.39 (95%CI 0.21, 0.72; I2 = 0%), depression OR = 0.81 (95%CI 0.72, 0.91; I2 = 0%) and fatigue OR = 0.62 (95%CI 0.41, 0.94; I2 = 75%) (Figure 4). Due to the small number of studies, a subgroup analysis could not be performed to address the heterogeneity in the prognostic factor fatigue (only one study was about cancer and only one study was a cohort study). Figure 4 Forest plot condition-related factors
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