305 Supplementary material | Appendix C A Outcome variables (measurement type) Assessment time Descriptive statistics of raw data Between-group effects TAU+FNC group TAU group Crude effect Adjusted effect 3 months 7.571 (10.345), n = 35 7.364 (11.341), n = 44 0.717 (0.368 to 1.400) 0.701 (0.365 to 1.345) 6 months 6.545 (9.217), n = 44 5.282 (9.671), n = 39 1.340 (0.713 to 2.516) 1.378 (0.752 to 2.523) 9 months 7.244 (10.535), n = 41 6.538 (10.558), n = 39 1.038 (0.496 to 2.172) 0.977 (0.494 to 1.933) 12 months 6.191 (9.253), n = 42 4.310 (7.588), n = 42 1.279 (0.597 to 2.738) 1.213 (0.586 to 2.514) 18 months 6.368 (9.604), n = 38 4.028 (7.606), n = 36 1.026 (0.470 to 2.239) 0.951 (0.452 to 2.001) Days cannabisb 1.462 (0.782 to 2.732)d 1.199 (0.680 to 2.112)d Baseline 9.000 (12.291), n = 51 8.765 (11.911), n = 51 3 months 9.829 (12.743), n = 35 6.227 (10.376), n = 44 1.564 (0.729 to 3.356) 1.298 (0.656 to 2.569) 6 months 9.250 (12.378), n = 44 5.846 (9.691), n = 39 1.126 (0.570 to 2.224) 0.942 (0.485 to 1.831) 9 months 9.488 (12.892), n = 41 5.718 (10.364), n = 39 1.870 (0.840 to 4.160) 1.499 (0.681 to 3.300) 12 months 8.857 (12.215), n = 42 5.000 (9.571), n = 42 1.875 (0.795 to 4.425) 1.650 (0.706 to 3.859) 18 months 10.342 (13.358), n = 38 6.108 (11.007), n = 37 1.001 (0.409 to 2.448) 0.741 (0.318 to 1.724) Days hard drugsb 0.612 (0.215 to 1.744)d 0.693 (0.278 to 1.727)d Baseline 2.078 (5.932), n = 51 0.412 (1.780), n = 51 3 months 2.514 (6.428), n = 35 0.136 (0.554), n = 44 1.999 (0.545 to 7.331) 2.482 (0.687 to 8.970) 6 months 2.295 (7.248), n = 44 0.897 (4.828), n = 39 0.277 (0.050 to 1.519) 0.345 (0.070 to 1.778) 9 months 2.244 (6.822), n = 41 0.615 (2.592), n = 39 0.651 (0.161 to 2.638) 0.931 (0.250 to 3.469) 12 months 0.810 (3.133), n = 42 1.071 (3.502), n = 42 0.539 (0.082 to 3.545) 0.418 (0.077 to 2.274) 18 months 2.237 (6.158), n = 38 0.405 (1.423), n = 37 0.998 (0.272 to 3.659) 1.123 (0.285 to 4.419) Quality of life (self-report)a -0.175 (-0.504 to 0.154)d -0.147 (-0.499 to 0.204)d Baseline 4.172 (1.106), n = 51 4.029 (0.964), n = 51 3 months 4.212 (1.219), n = 35 4.305 (1.072), n = 44 -0.090 (-0.525 to 0.345) -0.067 (-0.520 to 0.386) 6 months 4.308 (1.305), n = 44 4.524 (1.119), n = 39 -0.296 (-0.724 to 0.133) -0.270 (-0.717 to 0.178) 9 months 4.399 (1.261), n = 41 4.500 (1.040), n = 39 -0.085 (-0.518 to 0.348) -0.085 (-0.518 to 0.348) 12 months 4.611 (1.195), n = 42 4.701 (1.110), n = 42 -0.136 (-0.562 to 0.290) -0.112 (-0.556 to 0.333) 18 months 4.432 (1.319), n = 39 4.540 (1.066), n = 39 -0.344 (-0.781 to 0.092) -0.322 (-0.776 to 0.132) Self-sufficiency (observer-rated)a -0.001 (-0.141 to 0.138)d 0.023 (-0.124 to 0.169)d Baseline 3.440 (0.395), n = 51 3.424 (0.346), n = 51 3 months 3.466 (0.470), n = 35 3.517 (0.424), n = 44 -0.042 (-0.224 to 0.140) -0.020 (-0.208 to 0.168) 6 months 3.540 (0.535), n = 44 3.562 (0.527), n = 39 -0.005 (-0.184 to 0.174) 0.020 (-0.166 to 0.205) 9 months 3.580 (0.525), n = 41 3.645 (0.501), n = 39 -0.045 (-0.226 to 0.136) -0.024 (-0.210 to 0.163)
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