Thesis

148 Chapter 5 Table 2. Treatment effects on primary and secondary outcomes from intention-to-treat analyses (N = 102). Outcome variables (measurement type) Assessment time Descriptive statistics of raw data Adjusted effects TAU+FNC group TAU group Between-group effect Standardized effect size Primary outcome Mental wellbeing (self-report)a -0.193 (-0.434 to 0.047)d -0.187 Baseline 3.797 (0.967), n = 50 3.622 (1.146), n = 51 12 months 3.993 (0.926), n = 42 4.033 (1.196), n = 42 -0.151 (-0.484 to 0.182) -0.142 18 months 3.953 (0.918), n = 39 3.948 (1.062), n = 39 -0.234 (-0.578 to 0.111) -0.236 Key secondary outcomes Psychiatric functioning General psychiatric functioning (observer-rated)a -0,009 (-0.139 to 0.120)d -0.020 Baseline 0.866 (0.434), n = 51 0.891 (0.445), n = 51 12 months 0.772 (0.450), n = 42 0.764 (0.506), n = 42 -0.070 (-0.243 to 0.103) -0.147 18 months 0.757 (0.457), n = 37 0.785 (0.487), n = 38 -0.067 (-0.246 to 0.113) -0.143 Hospitalization Number in addiction and psychiatric care (self-report)b 0.976 (0.488 to 1.952)d NA 12 months 0.07 (0.261), n = 42 0.12 (0.400), n = 41 0.593 (0.133 to 2.647) NA 18 months 0.22 (0.584), n = 37 0.15 (0.362), n = 40 1.635 (0.558 to 4.790) NA Number in internal mental healthcare institute (medical record)b 12 months 0.167 (0.476), n = 48 0.192 (0.495), n = 47 1.020 (0.304 to 3.424) NA 18 months 0.271 (0.644), n = 48 0.234 (0.520), n = 47 1.016 (0.357 to 2.890) NA

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