Vascular risk factors for depression and apathy | Part II 106 Figure 1. Flow chart of the inclusion of studies Flow chart of the inclusio of studie Full‐text articles excluded, with reasons (n=13) No apathy (n=5) Stroke (n=3) Specific population: Depression (n=2) CADASIL (n=1) Cerebral amyloid angiopathy (n=1) Duplicate (congress publication of included article) (n=1) Studies included in qualitative synthesis (n = 14) Full‐text articles excluded, with reasons (n=16) No apathy (n=12) Dementia (n=2) Specific population: Depression (n=1) Subclinical apathy (n=1) Records identified through database searching (n=3536) Vascular apathy (n=10) Apathy and: Deep white matter hyperintensities (n=17) White matter hyperintensities (n=34) Cerebrovascular disease, not stroke (n=71) Lacunar infarcts (n=165) Cerebral microbleeds (n=28) Cortical thickness (n=183) Perivascular spaces (n=80) Ankle brachial pressure index (n=4) Intima media thickness (n=0) Arterial stiffness (n=36) Cardio‐femoral pulse wave velocity (n=0) Cerebrovascular risk factors (n=153) Hypertension (n=1911) Additional records identified through other sources (n=534) Reference lists of included articles (n=532) Alternative pathway (n=2) Records considered not relevant or duplicates (n=511) Full‐text articles assessed for eligibility (n=20) Duplicates removed (n=692) Considered not relevant (n=2824) Full‐text articles assessed for eligibility (n=23)
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