96 CHAPTER 6 data can be found in Supplemental table 1. After data collection, all data were processed in accordance with the General Data Protection Regulation on a dedicated research drive within the hospital’s digital storage system. All non- digital material, e.g. interview reports, were stored in a secured research archive. 6.2.4 Statistical analysis All datawere assessed for normality and visually inspected for quality assurance. Asmost data were non-normally distributed, outcomes are displayed asmedian [interquartile range, IQR] or n (%), depending on the variable type. Baseline and Table 1. Schematic overview of measurements during the study period Measurements Baseline (<72 hours after admission) ICU-stay Research visit (3,6,12m) Telephone interview by researcher (3,6,12m) One year Demographic factors x* Anthropometrics x* x Admission type x* Frailty category, pre-frail (CFS≥4) x* BIA-derived phase angle( ) x* Severity of illness (APACHE III-score) x* ICU LOS x* Days of mechanical ventilation x* Need for RRT in ICU x* Energy & protein intake x* x Feeding strategy x* x Rehabilitation activities x # visits dietician/SLT x Barriers for dietary intake x # ICU-readmissions x # hospital readmissions x 1-year mortality x Abbreviations: APACHE, acute physiology and chronic health evaluation; BIA, bioimpedance analysis; CFS, clinical frailty scale; ICU, intensive care unit; LOS, length of stay; SLT, speech & language therapist; RRT, renal replacement therapy. * Standard care
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