84 CHAPTER 5 (Table 1). Sixty-three percent of the patients were admitted after elective surgery. The median value of phase angle was 5.4 (4.6-6.4). There was no difference in baseline phase angle between patients whowere admitted after elective surgery or after acute admissions (p = 0.233). Of all patients, 115 (11%) died within a year after admission to the ICU. Non- survivors had higher APACHE III [86 (65-119) vs. 55 (46-67), p < 0.001]. ROC curve analysis determined the optimal phase angle cut-off value (Youden index), for the prediction of 1-year mortality was 4.6° (Figure.1). The area under the curve was 0.63 (95% confidence interval: 0.58-0.70) with a sensitivity of 80% and specificity of 49%. Univariate analysis showed an association between mortality and admission type, sepsis, presence of malignancy, APACHE III, and low PhA. Multivariate logistic regression analysis using these variables confirmed low PhA to be an Figure 1. ROC curve of phase angle. 1 - Specificity 1,0 0,8 0,6 0,4 0,2 0,0 Sensitivity 1,0 0,8 0,6 0,4 0,2 0,0 ROC Curve AUC = 0.63 (95% C.I. =0.58-0.70)
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