45 MENTAL FRAILTY IN ICU-SURVIVORS & INFORMAL CAREGIVER STRAIN 3 Table 1. Baseline and ICU-characteristics after group allocation at 12-months post-ICU. No mental frailty, n=149 (62%) Mental frailty, n=90 (38%) p-value Demographic factors Female, n (%) 57 (38) 35 (39) 0.992 Age 67 [57-73] 67 [57-74] 0.785 BMI 26.5 [24.3-29.4] 26.4 [23.5-30.1] 0.396 APACHE III 81 [60-101] 73 [56-91] 0.102 Comorbidities Medical comorbidity*, n (%) 64 (43) 48 (53) 0.119 Psychiatric history, n (%) 21 (14) 22 (24) 0.044 Depression 9 (6) 12 (13) 0.054 Bipolar disorder 0 1 (1) 0.197 PTSD 0 4 (4) 0.009 Anxiety disorder 2 (1) 4 (4) 0.137 Psychotic disorder 0 0 NA Personality disorder 3 (2) 2 (2) 0.913 Substance abuse 10 (7) 3 (3) 0.265 > 1 psychiatric disorder, n (%) 3 (2) 5 (6) 0.157 Aetiology Admission, n (%) Medical 70 (47) 51 (57) 0.343 Elective surgical 29 (19) 15 (17) Acute surgical 50 (34) 24 (27) Sepsis, n (%) 49 (33) 32 (36) 0.673 CPR, n (%) 30 (20) 15 (17) 0.506 ICU-morbidity LOS ICU 10 [6-20] 12 [6-23] 0.243 Mech. vent (days) 6 [3-12] 6 [3-17] 0.650 Delirium, n (%) 66 (44) 42 (47) 0.721 Abbreviations: APACHE, Acute Physiology and Chronic Health Evaluation; CPR, cardiopulmonary resuscitation; LOS ICU, Length of stay Intensive Care Unit; *Medical comorbidity: history of malignancy, diabetes, chronic obstructive pulmonary disease, stroke, and/or renal disease. Bold values indicate significant p-value.
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