28 CHAPTER 2 co-morbidities (i.e. presence of pre-existing comorbidities; p < 0.001). Furthermore, NR-patients had a longer LOS ICU, more days on mechanical ventilation, and a higher incidence of renal replacement therapy (p < 0.05). However, for patients in the R-group there was a higher incidence of cardiopulmonary resuscitation as primary reason for ICU-admission (p < 0.05). There were no differences in severity of illness score (APACHE III), admission type, and presence of sepsis (Table 2A). 2.3.3 Physical functioning at discharge and 3-months after ICU-admission NR-patients performed worse on physical functioning compared to R-patients at ICU-discharge with regards to functional status (p < 0.01) and muscle strength (p < 0.01). These differences persisted 3-months after ICU-admission (p < 0.001). Furthermore, NR-patients performed worse on walking distance, mobility and balance tests compared to R-patients 3-months after ICU- admission (p < 0.001). No significant difference in mobility was found between these patient groups at ICU-discharge (Table 2B). Figure 2. Median and 10-90th percentile of physical functioning domain score (RAND-36) of R and NR-patients at 3 and 12-months after ICU-admission. *** p<0.001. Physical functioning (RAND-36) (0-100%) Recovery (3m) Non-recovery (3m) Recovery (12m) Non-recovery (12m) 0 50 100 *** *** ***
RkJQdWJsaXNoZXIy MjY0ODMw