181 VR-THERAPY FOR UPPER EXTREMITIES MOBILISATION 8 8.3 RESULTS Of 12 eligible patients, ten patients gave permission to participate in this study. Nine patients completed the training. Patient characteristics are shown in Table 1. Four out of ten patients were diagnosed with comorbidities prior to ICU-admission; of those patients three had been diagnosed with chronic obstructive pulmonary disease and one with diabetes type 2. Clinical staff deemed patients capable to use the VR-headset after a median of five days of ICU-admission. Patients participated in three VR-therapy sessions per week with a median session duration of 20 min. and actual VR-gaming time ranging from 2 to 22 min. (Table 2). The remaining session time was used for preparation, giving the patient an introduction to the software, helping the patient to put on the VR-headset, selecting the game settings, resting if needed, interruption by other healthcare providers, and/or restarting VR-headset in case of technical difficulties. This resulted in session efficiencies ranging from 25% to 93%. To illustrate, patients 3 and 10 were very weak and therefore Table 1. Patient characteristics. ICU-patients (n=10) Age (years) 71 [63-79] Male 7 (70%) BMI (kg/m2) 27.1 [22.5-29.6] APACHE-III scorea 74 [66-104] Frailty scoreb,c 2 [2-3] Admission type Medical Elective surgery Acute surgery 6 (60%) 1 (10%) 3 (30%) Cardiopulmonary resuscitation 3 (30%) Sepsis 1 (10%) Medical comorbidities 4 (40%) Length of stay ICU prior to inclusion (days) 5 [4-10] Length of stay ICU (days) 6 [4-9] Length of stay hospital (days) 12 [10-19] Mechanical ventilation (days) 3 [3-7] Data are presented as median [IQR] or number (%). Abbreviations: ICU=Intensive Care Unit; APACHE=Acute Physiology and Chronic Health Evaluation . Notes: a Ranges from 0 to 299, with higher values representing a worse prognosis.31 b Ranges from 1 (very fit) to 9 (terminally ill).32 c Missing for five patients.
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