156 CHAPTER 7 Supplement 2. Continued. Study Design Title/reference Insufficient information on protein delivery or recommendation No difference in protein recommendation Other outcome Not eligible NRSI Other reason Zerbib 2021 NRSI Energy and protein intake in critically ill people with respiratory failure treated by high-flow nasal-cannula oxygenation: An observational study. Nutrition 84, (2021). X Zhu 2018 NRSI The Effect of IV Amino Acid Supplementation on Mortality in ICU Patients May Be Dependent on Kidney Function: Post Hoc Subgroup Analyses of a Multicenter Randomized Trial. Crit Care Med 46, 1293–1301 X Zusman 2016 NRSI Resting energy expenditure, calorie and protein consumption in critically ill patients: A retrospective cohort study. Crit. Care (2016). doi:10.1186/s13054-0161538-4 X Intervention: combined protein and exercise therapy Güngen 2017 NRSI Predictors of intensive care unit admission and mortality in patients with ischemic stroke: investigating the effects of a pulmonary rehabilitation program. BMC Neurol. 17, (2017). X X No ICU population Heyland 2019 RCT Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation commenced early during critical illness. BMJ Open 9, e027893 Published protocol
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