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146 CHAPTER 7 Supplement 2. Continued. Study Design Title/reference Insufficient information on protein delivery or recommendation No difference in protein recommendation Other outcome Not eligible NRSI Other reason Compher 2017 NRSI Greater Protein and Energy Intake May Be Associated With Improved Mortality in Higher Risk Critically Ill Patients: A Multicenter, Multinational Observational Study. Crit Care Med 45, 156–163 X CTR 2014 RCT Chinese Clinical Trial Registry (ChiCTRTRC-14005039). A prospective, randomized, comparative clinical trial to assess the effect and mechanism of glutaminesupplemented parenteral nutrition on surgical critically ill patients. Trial registration Czapran 2015 NRSI International observational study of nutritional support in mechanically ventilated patients following burn injury. Burns 41, 510–518 X deArruda 2004 RCT Benefits of early enteral nutrition with glutamine and probiotics in brain injury patients. Clin Sci 106, 287–292 X X Declerq 2016 NRSI Enhanced Protein-Energy Provision via the Enteral Route Feeding (PEPuP) protocol in critically ill surgical patients: a multicentre prospective evaluation. Anaesth Intensive Care 44, 93–98 X deKoning 2020 NRSI Association of PROtein and CAloric Intake and Clinical Outcomes in Adult SEPTic and Non-Septic ICU-Patients on Prolonged Mechanical Ventilation: The PROCASEPT Retrospective Study. J. Parenter. Enter. Nutr. 44, 434–443 (2020). X

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