589448-Beumeler

133 PROTEIN PROVISION AND EXERCISE THERAPY TO IMPROVE OUTCOMES IN ICU-SURVIVORS 7 Data items 10a List and define all outcomes for which data were sought. Specify whether all results that were compatible with each outcome domain in each study were sought (e.g. for all measures, time points, analyses), and if not, the methods used to decide which results to collect. 2.5 data extraction, 2.7 statistical analysis 10b List and define all other variables for which data were sought (e.g. participant and intervention characteristics, funding sources). Describe any assumptions made about any missing or unclear information. 2.5 data extraction; 2.7 statistical analysis Study risk of bias assessment 11 Specify the methods used to assess risk of bias in the included studies, including details of the tool(s) used, how many reviewers assessed each study and whether they worked independently, and if applicable, details of automation tools used in the process. 2.6 quality assessment Effect measures 12 Specify for each outcome the effect measure(s) (e.g. risk ratio, mean difference) used in the synthesis or presentation of results. 2.7 statistical analysis Synthesis methods 13a Describe the processes used to decide which studies were eligible for each synthesis (e.g. tabulating the study intervention characteristics and comparing against the planned groups for each synthesis (item #5)). 2.2 eligibility criteria 13b Describe any methods required to prepare the data for presentation or synthesis, such as handling of missing summary statistics, or data conversions. 2.7 statistical analysis 13c Describe any methods used to tabulate or visually display results of individual studies and syntheses. 2.7 statistical analysis 13d Describe any methods used to synthesise results and provide a rationale for the choice(s). If meta-analysis was performed, describe the model(s), method(s) to identify the presence and extent of statistical heterogeneity, and software package(s) used. 2.7 statistical analysis 13e Describe any methods used to explore possible causes of heterogeneity among study results (e.g. subgroup analysis, metaregression). 2.7 statistical analysis 13f Describe any sensitivity analyses conducted to assess robustness of the synthesised results. 2.7 statistical analysis Reporting bias assessment 14 Describe any methods used to assess risk of bias due to missing results in a synthesis (arising from reporting biases). 2.6 quality assessment Certainty assessment 15 Describe any methods used to assess certainty (or confidence) in the body of evidence for an outcome. 2.6 quality assessment

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