123 PROTEIN PROVISION AND EXERCISE THERAPY TO IMPROVE OUTCOMES IN ICU-SURVIVORS 7 Baseline characteristics (intervention / comparator) Main outcomes ICU-admission category (%) BMI Age APACHE II SOFA ICULOS Medical: Elective surgery: Emergency surgery: 79/59 8/13 13/27 24.6/28.4 70/ 68 23/24 7/ 8 15/ 16 Mortality Medical: Surgical: -/- -/- 21.3/22.2 65.6 69.4 17.8/18.6 6.8/ 7.2 6.5/ 10 Femoral muscle volume change, FSS-ICU, Barthel Index, EQ-5D Medical: Surgical: -/- -/- 21.3/20.9 70.2 66.0 19.1/17.7 6.7/ 6.9 8/ 7 EQ-5D, FSS-ICU, Barthel Index, femoral muscle volume change Medical: Elective surgery: Emergency surgery: 69/63 7/9 24/28 26.4/27.2 60.5 61.4 21.4/22.9 8.5/ 9.1 23.4/ 18.6 Mortality Respiratory: Sepsis: Other: 88/88 4/9 3/16 18.5/22.9 65/ 64 23.2/24.4 -/- 14/ 12 Mortality Trauma 100/100 25/23 53/ 60 15/ 14 -/- 10/ 5 Muscle depth change, Katz-ADL index, Barthel Index, MRC-ss Medical: Surgical/ trauma: 36/41 64/59 30.3/30.7 63.9 60.8 25/ 24 10/ 9 18.4/ 18.3 Nutritional delivery 1Intervention group=low NUTRIC score, comparator group=high NUTRIC score. 2Intervention: high protein (>1.2g/kg uncorrected bodyweight/day), comparator: low protein (<0.8g/kg uncorrected bodyweight/day). Intermediate protein group not reported in this table. Significant differences between groups in BMI, SOFA score, and surgical emergency admission. 3The study was included for both interventions (protein provision and combined protein-exercise therapy). 4Patients who stayed ≥4 days in the ICU (≥12 days not reported in this table). 5Intervention: adequate protein intake, comparator: inadequate protein intake, irrespective of energy intake (insufficient protein and adequate energy intake group not reported in this table). Significant differences in age, sex, CRP, BMI, C-reactive protein between groups.
RkJQdWJsaXNoZXIy MjY0ODMw