65 CHAPTER 3 GENETIC, ENVIRONMENTAL AND INTRINSIC DETERMINANTS OF THE HUMAN ANTIBODY EPITOPE REPERTOIRE Sergio Andreu-Sánchez1,2,*, Arno R. Bourgonje3,*, Thomas Vogl4,5,6, Alexander Kurilshikov1, Sigal Leviatan4,5, Angel J. Ruiz Moreno1, Shixian Hu1,3, Trishla Sinha1, Arnau Vich Vila1,3, Shelley Klompus4,5, Iris N. Kalka4, Karina de Leeuw7, Suzanne Arends7, Iris Jonkers1, Sebo Withoff1, Lifelines Cohort Study, Elisabeth Brouwer7, AdinaWeinberger4,5, CiscaWijmenga1, Eran Segal4,5, Rinse K. Weersma3,#, Jingyuan Fu1,2,#, Alexandra Zhernakova1,# 1Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands 2Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands 3Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands 4Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel 5Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel 6Diagnostic and Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University Graz, Graz, Austria 7Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands *,#These authors contributed equally Immunity 2022 (provisionally accepted)
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