256 Table 3. Correlations of fecal calprotectin levels (mg/kg) with serum levels of all detected molecules (pg/ mL) in patients with Crohn’s disease. *P-value < 0.05 was considered statistically significant; **P-value < 0.01. Chapter 7 Table 3. Correlations of fecal calprotectin levels (mg/kg) with serum levels of all detected molecules (pg/mL) in patients with Crohn’s disease. Detected molecules Spearman’s ρ P-value Pro-inflammatory panel IFN-γ 0.523 < 0.01** IL-1β 0.037 0.835 IL-2 -0.063 0.702 IL-4 0.111 0.526 IL-6 0.403 < 0.05* IL-8 0.033 0.844 IL-10 0.135 0.411 IL-12p70 0.071 0.676 IL-13 0.101 0.647 TNF-α 0.255 0.117 Cytokine panel GM-CSF 0.004 0.981 IL-5 0.148 0.374 IL-7 -0.005 0.974 IL-12/23p40 0.214 0.191 IL-15 0.088 0.596 IL-16 -0.018 0.914 IL-17A 0.352 < 0.05* TNF-β 0.396 < 0.05* Chemokine panel Eotaxin -0.003 0.986 MIP-1β -0.126 0.446 Eotaxin-3 -0.213 0.199 TARC -0.112 0.499 IP-10 0.207 0.207 MIP-1α 0.094 0.569 MCP-1 -0.025 0.878 MDC 0.088 0.593 Angiogenesis panel VEGF 0.019 0.907 VEGF-C -0.256 0.116 VEGF-D 0.004 0.980 Tie-2 -0.205 0.211 Flt-1 0.087 0.599 PIGF 0.023 0.888 bFGF -0.007 0.966 Vascular injury panel SAA 0.323 < 0.05* CRP 0.511 < 0.01** VCAM-1 0.148 0.367 ICAM-1 0.304 0.060
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